異槲皮苷結構式
|
常用名 | 異槲皮苷 | 英文名 | Isoquercitrin |
|---|---|---|---|---|
| CAS號 | 21637-25-2 | 分子量 | 464.376 | |
| 密度 | 1.9±0.1 g/cm3 | 沸點 | 872.6±65.0 °C at 760 mmHg | |
| 分子式 | C21H20O12 | 熔點 | 225-227° | |
| MSDS | N/A | 閃點 | 307.5±27.8 °C |
異槲皮苷用途Isoquercitrin 是一種有效的抗氧化劑和嗜酸性炎癥抑制劑。 |
| 中文名 | 異槲皮苷 |
|---|---|
| 英文名 | quercetin 3-O-β-D-glucofuranoside |
| 中文別名 | 羅布麻甲素 | 異櫟素 | 槲皮素-3-葡萄糖甙 | 槲皮素-3-O-葡萄糖苷 |
| 英文別名 | 更多 |
| 描述 | Isoquercitrin 是一種有效的抗氧化劑和嗜酸性炎癥抑制劑。 |
|---|---|
| 相關類別 | |
| 體外研究 | 異槲皮苷廣泛存在于植物中.7種化合物中的10μM異槲皮苷部分但顯著地減弱了H2O2對RGC-5細胞的負面影響,因為H2O2存在時細胞的存活率從大約63％增加到83％和90％分別為10和50μM時的％。實際上,50μM等槲皮苷作為神經保護劑比相同濃度的EGCG更有效[1]。 |
| 體內研究 | 在接受異槲皮苷或槲皮素的動物中,BALF,血液和肺實質中的嗜酸性粒細胞計數較低。血液中的中性粒細胞計數和肺勻漿中的IL-5水平僅在Isoquercitrin處理的小鼠中較低。沒有觀察到單核細胞數量的改變[2]。 |
| 動物實驗 | 免疫小鼠[2] BALB / c小鼠（卵清蛋白/氫氧化鋁，sc），然后進行兩次鼻內卵清蛋白攻擊。從第一次免疫后第18天到第22天，小鼠每天接受異槲皮苷（15mg / kg）或槲皮素（10mg / kg）的強飼。施用地塞米松（1mg / kg，sc）作為陽性對照。在最后一次卵清蛋白激發后24小時，在支氣管肺泡灌洗液（BALF），血液和肺實質中分析白細胞。白細胞介素-5（IL-5）在BALF和肺勻漿中進行分析[2]。 |
| 參考文獻 |
| 密度 | 1.9±0.1 g/cm3 |
|---|---|
| 沸點 | 872.6±65.0 °C at 760 mmHg |
| 熔點 | 225-227° |
| 分子式 | C21H20O12 |
| 分子量 | 464.376 |
| 閃點 | 307.5±27.8 °C |
| 精確質量 | 464.095490 |
| PSA | 210.51000 |
| LogP | 1.75 |
| 蒸汽壓 | 0.0±0.3 mmHg at 25°C |
| 折射率 | 1.803 |
| 儲存條件 | ?20°C |
| 安全聲明 (歐洲) | 24/25 |
|---|---|
| 危險品運輸編碼 | UN 2811 |
| WGK德國 | 3 |
| RTECS號 | LK8960000 |
| 異槲皮苷上游產品 0 | |
|---|---|
| 異槲皮苷下游產品 2 | |
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Isoquercitrin provides better bioavailability than quercetin: comparison of quercetin metabolites in body tissue and brain sections after six days administration of isoquercitrin and quercetin.
Pharmazie 67(12) , 991-6, (2012) In the present study, over a period of 8 days 12 mg/kg/d quercetin aglycone and 18 mg/kg/d isoquercitrin were orally given to rats, respectively. Four hours after administration, plasma samples were t... |
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A sensitive LC-MS/MS method for simultaneous determination of six flavonoids in rat plasma: application to a pharmacokinetic study of total flavonoids from mulberry leaves.
J. Pharm. Biomed. Anal. 84 , 189-95, (2013) A simple and sensitive LC-MS/MS method has been developed and validated for the determination of rutin, isoquercitrin, astragalin, quercetin, kaempferol and isorhamnetin in rat plasma using naringin a... |
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Complete 1H NMR spectral analysis of ten chemical markers of Ginkgo biloba.
Magn. Reson. Chem. 50(8) , 569-75, (2012) The complete and unambiguous (1)H NMR assignments of ten marker constituents of Ginkgo biloba are described. The comprehensive (1)H NMR profiles (fingerprints) of ginkgolide A, ginkgolide B, ginkgolid... |
| Quercetin 3-O-β-glucoside |
| trifoliin |
| 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl β-D-glucofuranoside |
| quercetin 3-O-β-D-glucopyranoside |
| Quercetin 3β-O-glucoside |
| 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3-(β-D-glucofuranosyloxy)-5,7-dihydroxy- |
| 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxy-phenyl)-3-(β-D-glucofuranosyloxy)-5,7-dihydroxy- |
| Quercetin 3-β-glucoside |
| Quercetin 3-O-glucofuranoside |
| 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl β-D-glucopyranoside |
| Isopseudopsoralen |
| isopseudopsoralene |
| Quercetin 3-β-D-glucoside |
| quercetin-3-glucoside |
| 3-O-β-D-Glucopyranosylquercetin |
| Quercetin glucoside |
| Isoquercitroside |
| Quercetin-3-O-β-D-glucoside |
| isopseudosporalen |
| Quercetin-3-O-β-glucopyranoside |
| Isoquercetrin |
| Quercetin 3-O-glucoside |
| Quercetin 3-D-glucoside |
| Isoquercitrin |
| isoquercetin |
| quercetin 3-O-β-D-glucoside |
| Hirsutrin |
| isotrifoliin |
| 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3-(β-D-glucopyranosyloxy)-5,7-dihydroxy- |
| 3,3',4',5,7-Pentahydroxyflavone 3-b-D-glucofuranoside |
| Quercetin-3-β-glucopyranoside |
| quercetin 3-O-beta-D-glucofuranoside |
| Quercetin-3-O-glucoside |
| Quercetin 3-β-O-glucoside |
| 2-(3,4-Dihydroxyphenyl)-3-(b-D-glucofuranosyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-one |
| Quercetin 3-O-glucopyranoside |
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